Du hast ihn anscheinend auch nicht gelesen

SchlauFuchs ⌂, Neuseeland, Dienstag, 14.07.2020, 23:33 (vor 2027 Tagen) @ Naclador2996 Views
bearbeitet von SchlauFuchs, Mittwoch, 15.07.2020, 00:00

Aber einen Autopsiebericht zu lesen, scheint die Presse sowohl in den USSA als auch in Europa zu überfordern.

Das wurde durchaus in der Presse diskutiert. Bloß dass 11ng/l Fentanyl keine Überdosis ist (oder Missbrauch belegt) sondern durchaus im Bereich einer üblichen Verschreibung liegt.

Hast du ihn gelesen? Wo steht da, er starb wegen Fentanyl?

Hier ein Artikel zu den Obduktionen:
https://www.newsweek.com/george-floyd-was-fentanyl-medical-examiner-says-experts-disput...

Hier was man zu Fentanyl wissen sollte:

Overdose results in respiratory depression which is reversible with naloxone. Sudden death can also occur because of cardiac arrest or severe anaphylactic reaction. The estimated lethal dose of fentanyl in humans is 2 mg. The recommended serum concentration for analgesia is 1–2 ng/ml and for anaesthesia it is 10–20 ng/ml.

https://thedailyblog.co.nz/2020/06/05/on-the-attempted-distraction-of-george-floyds-aut...
Saw some people posting about the (family) autopsy toxicology results for George Floyd. Specifically, 11ng/ml fentanyl, 5.6 ng/ml norfentanyl, 0.65 ng/ml 4-ANPP, and 19 ng/ml methamphetamine.
It’s easy to take a look at those, and just make an auto-leap; in fact, a series of auto-leaps. Either to the obvious “so that’s what killed him”, if you’re looking for an alternate causation that’s not knee-on-neck prime; or, more insidiously, “no great loss, then”, if you’re suddenly less bothered a man’s dead because that’s what the tox-screen says was in him.

Except here’s the thing. Those numbers are just that. Numbers. There’s no context to them – and no real way of checking, in the absence of better data, what they actually tell us or hide from sight.

They don’t necessarily support the conclusions some people are quite keen to jump to. And the fact that people citing them aren’t taking a bit more of a critical look before speaking, is concerning.

For a start – unless I’m mistaken, levomethamphetamine containing decongestants are still over-the-counter available in the U.S.

If he was suffering from Covid-19, it’s not unreasonable to presume he might have made use of just such a medication.

Even though it’s the other isomer from dextroamphetamine, it’ll still show up as meth in a lot of tox-screens.

Funnily enough, a few years back, an actress called Brittany Murphy had something like this happen. Died of pneumonia, and initially due to tox-screen results, it was also chalked up to polydrug intoxication .. with the usual “actress ODs” type inferences. Except that wasn’t really what happened – everything that turned up in the tox-screen was legally there, including the (levo)methamphetamine. She’d had an illness, taken something over-the-counter for it [in addition, to be sure, to several other medications for other conditions she was also suffering from at the time] … and yet if you just looked for the presence of methamphetamine in her system without understanding why it was there, you’d come away with the conclusion that she was a recreational practitioner of the glassware barbeque.

Back to George Floyd.

The level of meth stated to have been found in his blood – 19 nanograms per millilitre – is pretty low. However, in the absence of more and better data, we can’t really determine much more about this, in terms of why it might have been in his system, whether it’s a false positive, or simply an over-the-counter decongestant doing what it was supposed to do.

Although what I will say is that the lack of amphetamine (as opposed to methamphetamine) detected in his bloodstream, would support either a very low recent dose, or a somewhat larger dose some time ago (like, days); either because there’s been insufficient time for the meth to metabolize to amphetamine in the former possibility, or because enough time has passed that the meth metabolized to amphetamine has been eliminated from his system to a point below a detectable level leaving only residual meth.

As applies the fentanyl … there are further potential complications.

There are several legitimate psychiatric medications that can cause false-positives in tox-screens for fentanyl; although given the presence of norfentanyl and 4-ANPP, that’s perhaps less likely (but still not impossible).

Assuming that it’s not a false-positive, 11 nanograms fentanyl per millilitre of blood would be notably at the higher end of the therapeutic use spectrum (although significantly within the range wherein if it were to come up at an autopsy it would ordinarily be held to be ‘incidental’ to cause of death).

However, this is considerably complicated by a number of factors – including the way in which fentanyl (particularly if patch administered) stored in fat, muscle, skin etc. can start to leach into the bloodstream as tissue breaks down post-mortem. Which effectively means there’s no definitive way to tell post-mortem how much fentanyl was actually in the deceased’s bloodstream pre-mortem. [...]


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